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Keto Burn Extreme However, in the treatment of thromboembolic conditions , heparin is initially administered to patients due to the rapid onset of action, and vitamin K antagonists are used only after a few days as a continuation of treatment.vitamin K antagonists - monitoring of blood coagulation parametersFrequent blood laboratory tests and monitoring of coagulation parameters (specifically prothrombin time (PT) expressed as INR, or international normalized ratio (INR) is very important.Choosing the right dose of medicine is not a simple task and requires an individual approach to each patient. http://leoalexanderformayor.com/